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That rationale must be backed by non-clinical data confirming the compound behaves as expected and by a thorough safety and toxicology program that identifies potential risks and establishes a safe starting dose for the first human administration and the maximum human exposure that should not be surpassed

Pre-cycle testing Before starting IGF-1 LR3, establish baseline values for: Fasting glucose and insulin HbA1c (long-term blood sugar marker) IGF-1 levels Complete metabolic panel Lipid panel These baselines allow comparison during and after cycles to identify any negative trends

Ali ST, Jahangir S, Karamat S, Fabian WM, Nawara K, Kona J