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Recent research have showed that CD8 + T cells could enhance T cellmediated immunity and release IFN-, downregulate SLC7A11 to lead to ferroptotic cancer cell death ( Tetrastigma hemsleyanum polysaccharide (THP) regulated ferritin autophagy and ferroptosis in triple-negative breast cancer and improved the cancer microenvironment and immune function through increased CD4+ and CD8+ T cells as well as reduced regulatory T cells (Wang, 2024)

10.1038/nature07823 53 GaoR.-D.HinN.PrchalovE.PalA.LamJ.RaisR.et al (2021)

The drugs are administered in repeated cycles at regular intervals (Chabner 2013a)

Additionally, a bio-stimulatory filler such as Sculptra may be used