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Preclinical Studies Early preclinical studies in rodents and other animal models established that CJC-1295 could produce sustained elevations in growth hormone and IGF-1 levels lasting days after a single injection, in contrast to the brief elevations seen with native GHRH

In contrast, its paralog CHAC2 remains unresponsive, highlighting CHAC1s unique role in stress adaptation (Ward et al., 2024)

However, due to its potent effects and the current stage of research, its application should be carefully considered within a clinical setting, guided by comprehensive testing and professional oversight

Enslow BT, Stockand JD, Berman JM