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Its effects have been linked to endothelial nitric-oxide synthase (eNOS) and to VEGFR2-driven angiogenesis, and its influence on fibroblast outgrowth and migration is attributed to the FAKpaxillin signaling pathway

Conversely, emulsification creates capsules that may consist of either oil-based or water-based droplets (287)

Crystals of ShD14 were obtained by mixing 0.40 L of purified protein solution (6.9 mg mL 1 ) with 0.40 L of reservoir solution containing 100 mM CAPS (pH 10.0), 200 mM NaCl, and 20% (w/v) PEG8000 and allowing the drop to equilibrate at 20 C in 96-well Intelli-Plates (Art Robbins)