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Another proposed mechanism for platinum drug resistance is the formation of adducts between the platinum drug and the cysteinyl-glycine product of GT

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Activity-induced state fatigue is characterized by an acute and temporary change in motor or cognitive performance as well as the subjective experience of weariness or exhaustion that occurs in the context of a specific motor or cognitive task

The open-label, parallel-add-on, and match-controlled study demonstrated that administration of coenzyme Q10 at a dose of 100 mg/day (together with previously taken preventive drugs) resulted in a reduction of the frequency of migraine episodes and, simultaneously, shortening of the duration of a single episode