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The FDA-approved labels for GLP-1 receptor agonistsincluding semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide (Byetta, Bydureon)specify refrigeration as the primary storage method for unopened pens or vials

We know of two members of this society who use oral tablets instead of injections but they take enormous doses in order that, hopefully, some of what they swallow will be absorbed passively in their gut

These changes became more pronounced and consistent after 3-4 days of continued therapy [12]

Crucially, many trials may have included older adults, but had an upper age limit in their inclusion/exclusion criteria, resulting in little data for people in their 80s