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Through the reduction of mRNA and protein expression levels of NLRP3, ASC, GSDMD, and caspase 1, as well as the reduction of serum and ovarian levels of IL-18 and IL-1, moxibustion therapy, when administered to a rat model of CP-induced POF, demonstrated a significant suppression of NLRP3 activation (Yin et al

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Based Complement

Cells were exposed for 48 h, the cleared cell extracts were incubated with DEVD-p-nitroanilide and caspase-3 activity was measured spectrophotometrically