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Using invasive sampling methods, such as bronchoalveolar lavage (BAL) or transtracheal aspiration (TTA), the LRT has been shown to host a low-biomass core microbiota dominated by Pasteurellaceae, Mycoplasmataceae, Flavobacteriaceae, Clostridiaceae, and Prevotellaceae, while archaea, viruses, and eukaryotic microbes are rarely reported (Table 1) 8,110,111,112

While early and smaller trials showed promising fat-loss effects, the largest Phase IIb trial did not achieve statistical significance in humans for its primary endpoint of weight reduction, which led to the program being discontinued

Improves Collagen and Elastin Production Strengthens the structural matrix around follicles

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