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The symptoms of vitamin B12 deficiency can be quite debilitating and include, according to scientific research: Chronic fatigue and weakness Shortness of breath Heart palpitations Tingling or numbness in the extremities Poor balance Loss of concentration and poor memory Disorientation Mood changes, including depression Insomnia Imagine trying to maintain a healthy, active lifestyle when you're constantly battling severe fatigue and low energy

Additionally, in wild-type mice that overexpressed hHPN WT , there was a significant reduction in Cx32 expression, i.e., approximately 50 9% compared with both the AAV-hHPN RS and the vector-control (AAV-EGFP) groups (Fig

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