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acyl-CoAs are converted to acylcarnitines by CPT1 located on the mitochondrial outer membrane, which are translocated across the inner membrane by carnitine/acylcarnitine translocase (CACT) and reconverted to acyl-CoAs by CPT2 located on the inner membrane (Evans and Fornasini, 2003), (Longo et al., 2016)

Neurological Disorders Such as Alzheimers, Parkinsons, and multiple sclerosis, due to cumulative nerve damage

A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis

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