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In addition to dependence, several studies have also found that smoking during adolescence is also associated with a higher risk of developing mental and behavioral problems during adulthood

This section provides a high-level overview of some of the theoretical and empirical concepts about initiation and cessation of tobacco use among youth and adults and discusses characteristics of tobacco products, particularly their addictive nature, that are important to consider when developing a computational model

Microglia contact induces synapse formation in developing somatosensory cortex