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However, CCI rats treated with AST (10 mg/kg) demonstrated a significant improvement in myelin sheath integrity and Schwann cells

Immunohistochemistry (hair cell viability)Fixed and dissected cochleae are incubated in PBS-T with 10% normal goat serum with a phalloidin primary antibody overnight at 4 C

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The authors proposed that GPx2 disrupted the positive feedback loop of PGE 2 -dependent expression of COX-2, representing a unique role specific for GPx2 in the colon cancer model ( Reference Banning, Florian and Deubel 5 )