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Additionally, NAD+ has been shown to enhance the activity of PARP enzymes, which are involved in DNA repair

NAD+ is required for ATP production, and topping up a declining pool is the rationale [1]

NETosis NETosis is a distinctive form of programmed cell death exclusive to neutrophils, which captures and kills pathogens by releasing a network of DNA, histones, and antimicrobial proteins (neutrophil extracellular traps, NETs) [245]