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Referring to Rhodiola studies, numerous clinical trials were conducted in patients who were diagnosed with fatigue syndrome, aging cognitive deficiencies, mild/moderate depression, anxiety, and burnout symptoms, and in healthy subjects who experienced life stress-induced fatigue [17,18,19,42,287,288,289,290,291,292,293,294,295,296,297,298,299,300,301,302,303,304,305,306,307,308,309,310,311,312,313,314,315,316,317,318,319,320,321,322,323,324,325] and 84 reviews only on Rhodiola have been published since 2011 and confirm that Rhodiola preparations exhibit antifatigue, antidepressant, and ergogenic activity, shown by an improvement in both physical and mental performance

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