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Helping water move in and out of cells as well as regulating water balance and blood volume throughout the body

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overexpressed miR-340-5p in the myocardium by direct myocardial injection of AVV-9 containing miR-340-5p precursor, which targeted inhibition of MyD88 and thus restored declining GSH levels, alleviated insult of cardiac function and oxidative injury induced by sepsis in the hearts of mice [253]

The animal protocol was approved by the Animal Experiment and Laboratory Animal Management Committee of Capital Medical University (ethics approval number: AEEI-2020002), and all experimental procedures are in compliance with the US Guidelines for the Management and Use of Laboratory Animals