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1 Approximately one-third to 40% of a typical proteome is a metalloprotein, 2 and cells must ensure that the metalloproteome is metalated with integrity, defined by binding of the cognate or native metal under all growth conditions, yet is sufficiently plastic or adaptable, so as to effectively respond to metal limitation while avoiding metal toxicity

The symptoms are thought to be mediated by the central nervous system and treatments are aimed at calming down the nervous system thus reducing pain

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These qualities, combined with their ability to reduce inflammation and encourage tissue repair, make exosomes particularly promising for maternal health and postpartum recovery