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The three SNPs mentioned above are in strong linkage disequilibrium, which leads to common haplotypes of 1236 C :2677 G :3435 C and 1236 T :2677 T :3435 T (Wang et al., 2005)

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Using single-sample GSEA, we assigned each patient an OxPhos score using the Molecular Signatures Database (MSigDB) Hallmarks Oxidative Phosphorylation signature 39,40 and then split patients based on the cohort mean (Fig

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