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While the drug release of CAM-NLPs was slower than that of free peptides, the penetration and cellular uptake were both higher in the CAM-NLPs group [109]

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In addition to cytochrome c , other IMS proteins are also mobilized and released into the cytosol where they promote or counteract caspase activation and hence cell death ( Caenorhabditis elegans by triggering a unique pattern of gene expression that modulates stress sensitivity and promotes survival (Yee et al., 2014)

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