4.2 Acute inflammatory amplification phase: neutrophil recruitment, NETosis, and programmed cell death The recruitment and activation of IL-1 , TNF - , complement fragment C5a, and chemical factors produced by macrophages and synoviocytes lead to a rapid influx of neutrophils into the articular cavity, marking the peak of the local inflammatory response, shows more significant performance under high crystal load conditions
Glutathione is essential for skin health due to its antioxidant properties, detoxification capabilities, support for collagen production, and regulation of melanin production
*Cytokines: Signaling molecules that mediate and regulate immunity, inflammation and hematopoiesis *TNF: Tumor necrosis factor
The resulting PCR products were purified using AxyPrep Mag PCR Clean-Up Kit (Axygen, United States), validated by an Agilent 2,100 Bioanalyzer (Agilent Technologies, United States), and quantified using a Qubit 2.0 Fluorometer (Invitrogen, United States)