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Description

16-week on / 4-week off: Extends into the range of the Phase IIb trial duration while building in a recovery window

BDNF supports the survival and function of sensory and motor neurons, and its deficiency contributes to nerve degeneration

Therefore, further studies are needed

Studies have explored its potential involvement in nitric oxide (NO) signaling, growth factor modulation (including VEGF, FGF2, and EGF receptor pathways), and FAK-paxillin pathway activation