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BPC-157: Discovery and Regulatory History How BPC-157 traveled from a 1993 gastric-cytoprotection hypothesis at the University of Zagreb, through Pliva's PL14736 clinical program, to research-use-only status and a 2022 WADA Monitoring Program listing

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The evidence is mixed, with some studies suggesting DSIP does not induce tolerance while user reports sometimes indicate diminishing returns with daily use

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