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thus, modulators of the Wnt/-catenin pathway have emerged to improve the efficacy of different immunotherapeutic agents in combination therapy, a finding that has already been researched in preclinical models

A natural product T1, bis(4-hydroxybenzyl)sulfide, isolated from the Chinese herbal plant, Gastrodia elata , is a strong competitive inhibitor against mushroom tyrosinase (IC 50 = 0.53 M, K i = 58 6 nM), outperforms than kojic acid