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Evidence: Both rely largely on animal and preclinical data

PMID: 40651366 Biochem Biophys Res Commun Neutrophils suppress osteogenic differentiation of Gli1+ stem cells via neutrophil extracellular traps and contribute to bone loss in periodontitis

Interestingly, MRAB urine and skin isolates must contain significant levels of protein integrated within their biofilms, as evidenced by Proteinase K treatment (Figure 3B)