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Cigarette smoke was produced from unfiltered 1R3 reference cigarettes machine puffed twice per minute using a 70-mL, two-second puff and then diluted with air cleaned by a high-efficiency particulate air filter

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Therefore, it is important to acknowledge not only the key arguments of the message (i.e., e-cigarettes are less toxic than cigarettes), but also what the message looks like (i.e., whether or not there are certain visual cues on the message, such as a cloud of smoke) when testing its effectiveness

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