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We have reported that serum total IGF-I decreased 1 week and 3 months after bariatric surgery, whereas serum bioactive IGF-I remained unchanged during that period, and after 12 months, both variables returned to pre-surgery levels (117)

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3 Important safety information and common side effects Side effects The most common side effects of GHK-Cu Cream include: Mild redness Temporary tingling or warmth Dryness Mild irritation or sensitivity These side effects are typically mild and often go away on their own within a week or two