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To accomplish this, the trial was designed to focus on the assessment of objective endpoints such as small nerve fiber quantification by using both skin biopsy and corneal confocal microscopy and to relate these findings to semiobjective sensory testing by using QST, which directly assesses the effects of potential changes in cutaneous innervation

doi: 10.1097/MED.0b013e32834ec952 33 KushidaCALittnerMRMorgenthalerTAlessiCABaileyDColemanJJr.et al

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