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Fragrance & Flavour In North America, Castoreum and Castor derivatives are deemed GRAS, or Generally recognized as safe by the FDA and have no restrictions on % present in food products where Castor derivatives have been used for vanilla and raspberry flavouring

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For all omnibus analyses reported below, results that were significant with the Holm-Bonferroni correction remained significant (analyses not shown) after controlling for the following covariates (chosen because those who were abstinent versus continuing to smoke at 1 year post-quit differed on these variables at baseline): education (less than high school vs