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During the 19th month, the solution is the same as that of the 20th month, indicating that the solution during the 20th month represents GSH(t) during the menstrual cycle

Moreover, analytical SEC suggests that SnCE1 Y212A is properly-folded, however, in contrast to non-acetylated SnCE1 C256A it elutes as sole monomer indicating the mutation affects the oligomeric state (Supplementary Fig

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2.2 Lactate shuttle Lactate, the terminal glycolytic metabolite, functions as a versatile molecular shuttleintracellularly, intercellularly, and systemicallymodulating cellular bioenergetics and redox equilibrium while accumulating across tissues via circulatory transport ( The aforementioned glycolytic reprogramming drives profound lactate and proton accumulation