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Within controlled laboratory settings, 5-Amino-1MQ is utilized to study how NNMT inhibition alters intracellular nicotinamide handling and affects downstream metabolic signaling pathways, including those related to NAD+ homeostasis, mitochondrial dynamics, and adipocyte functionality

In the present study, the cecal microbiome differed significantly across treatment groups, despite tightly controlling for several variables known to alter the microbiome in rodents

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