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scRNA-seq analysis of AS-derived endometrial organoids has identified significant gene expression alterations, particularly in WNT and NOTCH signaling pathways, mirroring changes seen in the in vivo endometrium [79]

Additionally, extreme dietary interventions should be approached with caution and implemented under the supervision of qualified healthcare professionals, particularly because it is uncertain if they might exacerbate symptoms in ME/CFS patients, especially during the initial weeks

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