Freire T, Robello C, Soul S, Ferreira F, Osinaga E
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Disclosure of interest: Baoshan Qiu: nothing to disclose Poster session II - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.09 - SEX, GENDER AND STROKE P935 - ESOC25-944 SEX DIFFERENCES IN CHARACTERISTICS, STROKE CARE AND OUTCOMES FOLLOWING SPONTANEOUS INTRACEREBRAL HEMORRHAGE: A POPULATION-BASED STUDY Anna Ramos-Pachon 1 , lvaro Lambea-Gil 1 , Joan Mart-Fbregas 1 , Luis Prats-Snchez 1 , Pol Camps Renom 1 , Marina Guasch-Jimnez 1 , Garbie Ezcurra 1 , Joan Miquel Fernandez Vidal 1 , Alejandro Martinez Domeo 1 , Mikel Terceo, Marc Puig Casadevall 2 , Yolanda Silva 2 1 Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 2 Hospital Universitari Dr

In the serum, Fe 2+ is oxidized by ceruloplasmin to Fe 3+ and then binds with transferrin (TF) to form a TFFe 3+ complex, which is endocytosed through the cell membrane transferrin receptor 1 (TFR1) ( 3+ is reduced to Fe 2+ , and the latter is transported out by the divalent metal ion transporter 1 (DMT1) or the zinc-iron-regulatory protein family 8/14 (ZIP8/14) ( 2+ is involved in the unstable iron pool (LIP)