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Glutathione levels regulate redox changes to nuclear proteins necessary for th initiation of cell differentiation where a less specialized cell becomes a more specialized one

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The psychological stress of managing a dramatic body transformation, dealing with GI side effects, adapting to new eating patterns, and the anxiety about potential side effects like hair loss, can itself trigger or worsen telogen effluvium

The efficacy of pseudocatalase foam applied twice daily with NB-UVB twice weekly for 24 weeks has also not been proven [119], but in a study combining pseudocatalase cream twice daily with UVB irradiation and calcium chloride, complete repigmentation occurred on the face and dorsum of the hands in 90% of patients [120]