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Therefore, therapeutic strategies that target the distinct mitochondrial metabolic features of CSCs and DTPs, such as disrupting the AMPKOXPHOS axis, inhibiting mitophagy, or decoupling metabolic signaling from DNA repair, represent a promising approach to overcoming chemoresistance in CRC

[DOI] [PubMed] [Google Scholar] 98.Hicks L.M., Cahoon R.E., Bonner E.R., Rivard R.S., Sheffield J., Jez J.M

All subjects were divided into different groups, where one group was presented with the peptide gel, whereas others were given standard care with a placebo application

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