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Many transaminases use pyruvate as the acceptor keto-acid, forming alanine, and there is an active alanine-glyoxylate transaminase in peroxisomes that transfers the amino group onto glyoxylate, forming glycine, which is then a substrate for glycine oxidase

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[108] [109] For example, the enzyme nicotinamidase, which converts nicotinamide to nicotinic acid, is a target for drug design because this enzyme is absent in humans but present in yeast and bacteria