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It helps prepare the body for pregnancy

Chronic hypoxia for 7 or 14 d, but not 1 or 3 d, resulted in alpha-synuclein hyperphosphorylation at serine129 (-Syn p-S129) and protein aggregation, hippocampal neurodegeneration, and cognitive deficits, whereas the latter could be prevented by alpha-synuclein knockdown or an administered short peptide competing at -Syn S129

The reality is nuanced: the clinical significance of elevated B12 depends almost entirely on why its elevated

There is a downregulation of proteins involved in pericyte-endothelial cell communication [76,77,78] and astrocytes, being a glia cell, become activated