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Self-reported community protocols commonly describe once-daily dosing with on/off cycling, motivated partly by the absence of any long-term human safety data and partly by a community perception of diminishing returns or tolerance over continued use

Such strategies that characterize bioactivation potentials in the context of drug metabolism, pharmacokinetic properties, clinical dose and additional risk factors have been proposed and successfully applied across the pharmaceutical industry

Dosage Guidelines The objective of this dosing regimen is to mitigate the effects of aging and age-related diseases through a targeted "cell cleansing" approach

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