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With years of empirical support, this hypothesis proposes that cocaine is a very rewarding and potentially addictive drug in part because it evokes a uniquely large dopamine response in the ventral striatum [6,7,8]

The genetic relationship between cannabis and tobacco cigarette use in European- and African-American female twins and siblings

However, the researchers also found something very surprising: in the cannabis/tobacco-using group the reverse was true, and smaller hippocampal volume correlated with improved memory