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doi: 10.2174/0122115560332182241031050521 41

It sends out the memo (IGF-1) and provides the budget (metabolic support) for growth and repair across the entire organization

In addition to a local effect, dietary Gln supplementation has been described to cause an increase of the systemic Gln concentration, which may also sustain the health and function of immune and epithelial cells 39

In 2018, a 39 amino-acid peptide tirzepatide (LY3298176) was developed, which is similar in size to both GLP-1 and GIP with exenatide-derived C-terminal tail and thus has a prolonged half-life