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The compound's selectivity profile minimizes concerns about off-target effects, but investigators should consider potential interactions with other NAD+-modulating interventions or compounds that affect methylation metabolism

Metformin, commonly prescribed for diabetes, and proton pump inhibitors used for acid reflux can both reduce B12 absorption over time

You may receive the shots in the arm or other areas containing more subcutaneous fatty tissues, such as the thigh, abdomen, or buttocks

[1] Without intrinsic factor, dietary B12 cannot be absorbed effectively, leading to deficiency regardless of dietary intake