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Colchicine has been shown to induce reversible malabsorption of vitamin B12, apparently by altering the function of ileal mucosa

Dietary intake: Vegetarians, vegans, and those who limit their daily consumption of animal products may have to consume more vitamin B12, as it is mainly present in foods of animal origin

Babula JJ, Bui D, Stevenson HL, Watowich SJ, Neelakantan H