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PMC 6632124

Those who with neuropathy present with a warm, swollen, red foot requires a thorough work up for possible charcot neuroarthropathy, nonweight bearing and urgent referral to a foot care specialist to prevent foot deformities and instability leading to ulcerations and amputations

47 Heme oxygenase 1 (HO-1) is an iron-dependent antioxidant enzyme, with its expression and activity upregulated by Nrf2

A la difference de la grande majorit des peptides, qui sont rapidement degrades par l'acide chlorhydrique et les enzymes proteolytiques de l'estomac, le BPC-157 conserve son intgrit structurale a des pH extremement bas (pH 1-2)