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References [1] National Library of Medicine, Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts, Chang, C., Tsai, W, Hsu, Y, Pang, J.S., 2014 [2] National Library of Medicine, Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review, Vasireddi, N., Hahamyan, H., Salata, M., Karns, M., Calcei, J., Voos, J., Apostolakos, J., July 2025 [3] National Library of Medicine, Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts, Chang, C., Tsai, W., Hsu, Y., Pang, JS., November 2014

Both the EPAC2 and PKA are activated in response to elevated cAMP [54]