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416 Purinergic receptor P2X7 (P2RX7) is a major driver of NLRP3 inflammasome activation and IL-1 processing

Tartaglia LA, Pennica D, Goeddel DV (1993) Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor

Mark Heyman got sick when he was 36 (chronic fatigue syndrome) He went from being super healthy to not knowing where he was at the end of a sentence and not being able to walk up the stairs Doctors told him he was depressed and to take Prozac He had lived in China for a year and was exposed to tons of mercury from coal burning His gut broke down, he had diarrhea for years His cognitive function completely went south he had dementia, ADD, and depression at once He met a guy who introduced him to Jeff Bland, who studied with Linus Pauling Jeff had a different view of health as a system Functional medicine looks at the body as connected, not just individual parts 00:08:51 Metabolic Psychiatry

Through these mechanisms, BPC-157 has been explored in research examining the coordination between vascular signaling, cellular migration, and structural tissue recovery