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Genome Res 19:15071515 Tujios S, Fontana RJ (2011) Mechanisms of drug-induced liver injury: from bedside to bench

Notably, brain accumulation of these compounds was significantly increased in ischemic models, attributable to compromised blood-brain barrier integrity

45 Gastrointestinal side effects are the most frequently reported side effects associated with oral zinc supplementation, 46 the most common among them being nausea reported in up to 25 percent of patients