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Rascol O, OryMagne F, Meissner WG, Maltte D, Defebvre L, Azulay J, et al

Tirzepatide trials (SURMOUNT-1) lasted 72 weeks

People often notice improvements in: Recovery speed: soreness resolves faster and training consistency improves Range of motion: tissue compliance improves without the same tightness rebound Stability: joints feel more dependable during load Resilience: flare cycles become less frequent and less intense Confidence: movement feels safer, which improves adherence to rehab and training The key is that the goal shifts from short-term symptom relief to long-term tissue resilience

Melasma usually fades after a few months