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The theory goes like this: Tyrosinase Inhibition: High levels of glutathione have been shown in some in vitro (test tube) and dermatological studies to interfere with tyrosinase activity

The phase 3 TRIUMPH-4 data showed these rates at 9 mg and 12 mg doses respectively: Nausea: 38.1% and 43.2% (vs 10.7% placebo) Diarrhea: 34.7% and 33.1% (vs 13.4% placebo) Constipation: 21.8% and 25.0% (vs 8.7% placebo) Vomiting: 20.4% and 20.9% (vs placebo) These numbers are higher than cagrilintide monotherapy across the board

Together, these suggest that AHKCu helps maintain a larger, healthier pool of dermal papilla cells, thereby driving follicle activity

Statistical analysis StataIC 16 was used for the main and subgroup analyses