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The reported outcome of this campaign was a candidate that retained agonist activity at amylin/calcitonin-family receptors while displaying a markedly extended pharmacokinetic profile in the authors' preclinical models, and reduced food intake in rodent models following administration

(2011) Corneal confocal microscopy: a novel non-invasive technique to quantify small fibre pathology in peripheral neuropathies

Abscence of detectable Philadelphia chromosome (Ph+) and Bcr/Abl positive cells in lin- SP bone marrow progenitor cells from patients with CML

Glutamine regulates CSCs through signaling pathways such as the mTOR and Notch