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Resistant / Refractory Melasma For cases that do not respond to standard care, dermatologists may combine oral tranexamic acid, advanced topicals (such as newer agents like thiamidol or malassezin), RF microneedling, or carefully selected picosecond lasers

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Collateral effects of antibiotics on mammalian gut microbiomes

46 Functionally, the adventitia is able to damp and dissipate energy during pulse loading and prevent the vascular wall from overexpansion