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2025), including proteases, phospholipases, neurotoxins, and procoagulant toxins, which damage the body through various mechanisms such as tissue necrosis, hemorrhage, neurological dysfunction, and coagulation disorders (Offor and Piater 2024)

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Research indicates FOXO4-DRI treatment does not compromise the chondrogenic capacity of retained cells, though additional interventions may enhance cartilage matrix production following senescent cell clearance

Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates