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Smokers can affect the amount of nicotine (and accompanying toxicants) they draw from a cigarette by altering the number of puffs taken, puff size, frequency, duration, and velocity (collectively referred to as smoking topography)

Darwiniana 50 , 207211 (2012)

The e-cigarette aerosol that users breathe from the device and exhale can contain harmful and potentially harmful substances, including: Nicotine Ultrafine particles that can be inhaled deep into the lungs Flavorings such as diacetyl, a chemical linked to a serious lung disease Volatile organic compounds Cancer-causing chemicals Heavy metals such as nickel, tin, and lead The Congressional Findings in the Tobacco Control Act, Surgeon Generals Reports, and other authoritative scientific studies have reported the following: Smoking costs the United States $193 billion every year from health care costs and lost productivity from premature death

Use of any form of tobacco was higher among boys than girls